منابع مشابه
Cold ischemia-induced autophagy in rat lung tissue
Autophagy is a highly conserved pathway that permits recycling of nutrients within the cell and is rapidly upregulated during starvation or cell stress. Autophagy has been implicated in the pathophysiological process of warm ischemia‑reperfusion injury in the rat lung. Cold ischemia (CI) preservation for lung transplantation also exhibits cell stress and nutrient deprivation, however, little is...
متن کاملEffects of Cold Ischemia Time on Hepatic Allograft Function
BACKGROUND Cold ischemia time is related to success of liver transplantation. AIM To compare the impact of cold ischemia time on allografts locally collected to those collected distantly. METHODS Were evaluated 83 transplantations. The patients were divided in two groups: those who received liver grafts collected from c...
متن کاملImpact of Cold Ischemia Time in Kidney Transplants From Donation After Circulatory Death Donors
BACKGROUND Deceased-donor kidneys are exposed to ischemic events from donor instability during the process of donation after circulatory death (DCD). Clinicians may be reluctant to transplant DCD kidneys with prolonged cold ischemia time (CIT) for fear of an additional deleterious effect. METHODS We performed a retrospective cohort study examining US registry data between 1998 and 2013 of adu...
متن کاملProlonged cold ischemia time obviates the benefits of 0 HLA mismatches in renal transplantation.
HYPOTHESIS Recipients of 0 HLA mismatch kidneys with prolonged cold ischemia times of longer than 36 hours do not have superior outcomes compared with recipients of kidneys with 1 or more mismatches. DESIGN Retrospective review. SETTING Transplanation centers. PATIENTS AND METHODS A total of 63,688 recipients who underwent transplantation between January 1, 1990, and July 31, 1998. MAIN...
متن کاملInfluence of Cold Ischemia Time in Kidney Transplants From Small Pediatric Donors
BACKGROUND Clinicians may be reluctant to transplant small pediatric kidneys that have prolonged cold ischemia time (CIT) for fear of an additional deleterious effect because pediatric grafts are thought to be more sensitive to ischemia. We aimed to assess the risks associated with transplantation of small pediatric kidneys with prolonged CIT. METHODS We performed a retrospective cohort study...
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ژورنال
عنوان ژورنال: Scientific Reports
سال: 2017
ISSN: 2045-2322
DOI: 10.1038/s41598-017-11284-z